Hormone Testing in Cosmetics

(1):Product type: focus on cream lotion, facial mask, gel, liquid water-based, liquid oil-based cosmetics; Extended to freckle whitening, acne removal, wrinkle resistance and firming, repair, infant and toddler cosmetics, and special cosmetics.

(2):Testing objects: finished cosmetics, semi-finished products, functional ingredients, and formula intermediates.

(3):Applicable scenarios: raw material entry screening, formula research and development verification, registration and filing inspection, market supervision sampling, safety risk assessment, consumer complaint detection, production process quality control.

(1) Core detection categories (mainly 63 banned hormones)
Corticosteroids (41 core types): Hydrocortisone, Cortisone, Prednisone, Prednisolone, Methylprednisolone, Betamethasone, Dexamethasone, Triamcinolone Acetonide, Fluconazole, Fluamethasone, Beclomethasone, Desonide, Flunidazole, Lumetazone, Triamcinolone, Isoflurprednisolone, Fluhydrocortisone, Flumipramide, Various Acetate Derivatives (such as Hydrocortisone Acetate, Prednisolone Acetate, etc.).
Sex hormones (7 core types): estradiol, estrone, estriol, estradiol, testosterone, methyltestosterone, progesterone.
Synthetic metabolic hormones and others: Norone, androstenedione, pregnenolone, medroxyprogesterone acetate, etc.

(2) Testing technical indicators
Qualitative screening: to confirm the presence of prohibited hormone components.
Quantitative determination: Accurately determine hormone content, with a detection limit typically ≤ 0.03 μ g/g and a quantification limit ≤ 0.1 μ g/g.
Method validation: Recovery rate (85% -115%), precision (relative standard deviation ≤ 5% -7%), elimination of matrix interference, and separation of isomers.